I need a system to handle my employee payroll.

I've worked with/for many companies over the past 4 decades, and have come to several conclusions about payroll:
1- never do it yourself - the exposure to compliance and legal issues is simply too great
2- currently the best-known names in the business (the three public companies), are haunted by either service or software problems to the extent that I no longer recommend them to my clients
3-Use a smaller company that has a tested, on-line system so you can access you payroll from where/whenever. I currently work with only three, two of which are local to Northern California. One is national

If you have the right back office accounting software (like Microsoft Dynamics GP) you really don't need to be afraid of doing your payroll in house.
If you choose to do inhouse or with a company like Paychex or ADP, you still need to sit in front of a computer screen and enter employee records. Just depends on if you are entering then into your accounting software or ADP screen. I admit, if you do it in house the extra step is that you have is to calculate checks, bill checks and print checks. But These 3 functions typically take no more than 1 to 2 hours. "But ADP will file my taxes!" you say. This is true. But if you purchase a one time add on to Dynamics GP called Greenshades, then the taxes are calculated for you in house also. All you have to do is send out the payment to the IRS. (I admit, an important step!)
In our experience, on average a company that pays 300-400 employees running payroll in house will spend approx. 3-4 hours extra per week vs. paying an outsourced company like ADP to do this for you.
We have one client, a staffing co in NYC, that processes 800 payroll checks weekly. They paid $205,000 each year to ADP. They purchased Microsoft Dynamics GP with payroll and the Greenshades product for a total of approx. $100,000. A one time purchase. Quite a savings year after year.
So before your are too quick to write it off as an option - consider spending your money on a good accounting software and doing your payroll internally.
check out microsoft dynamics gp at www.calszone.com

If you have not picked a company yet. I encourage you to look at ours. Visit our payroll page on our website at http://www.hrallencs.com/content/payrollservices. If you have any questions, please contact me at 916-370-7849 or mallen@hrallenconsulting.com.
We are capable of supporting up to 150 employees and our service is nation wide.